Today's new puzzle features a close-up of a pomegranate fruit. The pomegranate is widely considered to have originated in the vicinity of Iran and has been cultivated since ancient times. he pomegranate juice can be very sweet or sour, but most fruits are moderate in taste, with sour notes from the acidic tannins contained in the aril juice. Pomegranate juice has long been a popular drink in Armenian, Persian and Indian cuisine. Grenadine syrup is thickened and sweetened pomegranate juice and is used in cocktail mixing. Wild pomegranate seeds are used as a spice known as anardana (from Persian: anar + dana, pomegranate + seed), most notably in Indian and Pakistani cuisine, but also as a substitute for pomegranate syrup in Persian cuisine. Laboratory research and clinical trials found that juice of the pomegranate may be effective in reducing heart disease risk factors, including LDL oxidation, macrophage oxidative status, and foam cell formation.